Molecular mechanism of intraductal papillary mucinous neoplasm and intraductal papillary mucinous neoplasm-derived pancreatic ductal adenocarcinoma
نویسندگان
چکیده
منابع مشابه
Intraductal papillary mucinous neoplasm.
A 75-year-old male with a history of dyslipidemia, no alcohol abuse, acute pericarditis and two pancreatitis episodes 16 and 3 years ago, consulted due to a new pancreatitis episode (amylase 536 IU/l). Abdominal CT and MRI showed irregular, rosary-like dilatation of the duct of Wirsung in the body and tail (Fig. 1). In the pancreatic body-tail, echoendoscopy revealed a 15-mm duct of Wirsung wit...
متن کاملEvaluation of SOX9 expression in pancreatic ductal adenocarcinoma and intraductal papillary mucinous neoplasm.
OBJECTIVES Sex-determining region Y (SRY) box 9 (SOX9) is an important transcription factor required for development and has been implicated in several types of cancer. Sex-determining region Y box 9 has never been linked to pancreatic ductal adenocarcinoma (PDAC) and intraductal papillary mucinous neoplasm (IPMN) of the pancreas. The aim of this study was to investigate the relationship betwee...
متن کاملDiffuse replacement of pancreatic parenchyma by intraductal papillary mucinous neoplasm.
A 63-year-old insulin-dependent diabetic womanpresented to ourmultidisciplinary group for evaluation and management of multifocal cystic lesions of the pancreas found incidentally by computed tomography during an evaluation of diverticulitis. Initial assessment included endoscopic ultrasound (EUS) with fine-needle aspiration (FNA) by curved linear array echoendoscope. Near-total replacement of ...
متن کاملPancreatic carcinosarcoma mimics malignant intraductal papillary mucinous neoplasm
RATIONALE Carcinosarcoma, an extremely rare pancreatic primary tumor, is characterized by coexistence of both carcinomatous and sarcomatous components. Due to its rarity, the clinical manifestation and imaging features have not been recognized. An accurate diagnostic method has not been available and a widely accepted guidelines instructing treatment has not been established. PATIENT CONCERNS...
متن کاملfocus on the intraductal papillary mucinous neoplasm of the pancreas
intraductal papillary mucinous neoplasms (ipmns) are rare pancreatic tumours, accounting for less of 1-2% of all neoplasms of the gland. main characteristics of ipmns are their favourable prognosis as these pre-malignant or frankly malignant lesions are usually slow-growing tumours and radical surgery is frequently possible. according with the localization of the lesions, three different entiti...
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ژورنال
عنوان ژورنال: Journal of Hepato-Biliary-Pancreatic Sciences
سال: 2015
ISSN: 1868-6974
DOI: 10.1002/jhbp.246